{"id":27893,"date":"2025-12-11T09:14:00","date_gmt":"2025-12-11T09:14:00","guid":{"rendered":"https:\/\/pickbydoc.com\/251211040438-htm\/"},"modified":"2025-12-11T09:14:00","modified_gmt":"2025-12-11T09:14:00","slug":"251211040438-htm","status":"publish","type":"post","link":"https:\/\/pickbydoc.com\/?p=27893","title":{"rendered":"Gene-edited CAR-T cells erase aggressive T-cell leukemia"},"content":{"rendered":"<p>A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves\u2014a long-standing challenge in T-cell\u2013based therapies. Early trial results show deep, long-lasting remissions, including in patients who had exhausted standard treatment options.<\/p>\n<hr>\n<p>\n<strong>Source:<\/strong><br \/>\n<a href=\"https:\/\/www.sciencedaily.com\/releases\/2025\/12\/251211040438.htm\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nwww.sciencedaily.com<br \/>\n<\/a>\n<\/p>\n<p style=\"font-size:13px;color:#666;\">\n<strong>Medical Disclaimer:<\/strong><br \/>\nThis content is shared for informational and educational purposes only.<br \/>\nIt does not constitute medical, legal, or policy advice.<br \/>\nHealthcare decisions should always be made in consultation with qualified professionals.\n<\/p>\n<p><br \/>\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest forms of blood cancer, T-cell acute lymphoblastic leukaemia. By precisely rewriting tiny sections of DNA, scientists at UCL and Great Ormond Street Hospital created universal CAR T-cells capable of targeting the cancer without harming themselves\u2014a long-standing [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":27894,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[171],"tags":[10808,18642,11250,18643,16914,11659,18644],"class_list":["post-27893","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions","tag-aggressive","tag-cart","tag-cells","tag-erase","tag-geneedited","tag-leukemia","tag-tcell"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/27893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27893"}],"version-history":[{"count":0,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/27893\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/media\/27894"}],"wp:attachment":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}