{"id":27454,"date":"2023-02-09T16:47:00","date_gmt":"2023-02-09T16:47:00","guid":{"rendered":"https:\/\/pickbydoc.com\/230209114732-htm\/"},"modified":"2023-02-09T16:47:00","modified_gmt":"2023-02-09T16:47:00","slug":"230209114732-htm","status":"publish","type":"post","link":"https:\/\/pickbydoc.com\/?p=27454","title":{"rendered":"&apos;Tiny but mighty&apos; gene fragments are crucial for maintaining blood glucose levels"},"content":{"rendered":"<p>Microexons, tiny fragments of genes that are just 3-27 nucleotides long, are known to play a &#8216;tiny but mighty&#8217; role in neuronal cells. Through RNA splicing, microexons sculpt the surfaces of proteins in a highly precise manner, performing microsurgery on the nervous system&#8217;s proteins. According to a new study, microexons are also crucial for pancreatic function and regulating blood glucose levels. The microexons are located on more than a hundred genes, including some critical for insulin secretion and type-2 diabetes risk. The researchers believe the discovery could lead to new high-precision treatments for type-2 diabetes, for example by repurposing existing treatments that already exploit RNA splicing mechanisms to treat other types of diseases.<\/p>\n<hr>\n<p>\n<strong>Source:<\/strong><br \/>\n<a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/02\/230209114732.htm\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nwww.sciencedaily.com<br \/>\n<\/a>\n<\/p>\n<p style=\"font-size:13px;color:#666;\">\n<strong>Medical Disclaimer:<\/strong><br \/>\nThis content is shared for informational and educational purposes only.<br \/>\nIt does not constitute medical, legal, or policy advice.<br \/>\nHealthcare decisions should always be made in consultation with qualified professionals.\n<\/p>\n<p><br \/>\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microexons, tiny fragments of genes that are just 3-27 nucleotides long, are known to play a &#8216;tiny but mighty&#8217; role in neuronal cells. Through RNA splicing, microexons sculpt the surfaces of proteins in a highly precise manner, performing microsurgery on the nervous system&#8217;s proteins. According to a new study, microexons are also crucial for pancreatic [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":27455,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[171],"tags":[18267,3084,13897,18269,12465,3082,7526,18270,18268],"class_list":["post-27454","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions","tag-apostiny","tag-blood","tag-crucial","tag-fragments","tag-gene","tag-glucose","tag-levels","tag-maintaining","tag-mightyapos"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/27454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27454"}],"version-history":[{"count":0,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/27454\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/media\/27455"}],"wp:attachment":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}