{"id":26561,"date":"2026-01-28T14:10:00","date_gmt":"2026-01-28T14:10:00","guid":{"rendered":"https:\/\/pickbydoc.com\/260128075323-htm\/"},"modified":"2026-01-28T14:10:00","modified_gmt":"2026-01-28T14:10:00","slug":"260128075323-htm","status":"publish","type":"post","link":"https:\/\/pickbydoc.com\/?p=26561","title":{"rendered":"The hidden reason cancer immunotherapy often fails"},"content":{"rendered":"<p>Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research reveals a hidden trick: cancer cells can package the immune-blocking protein PD-L1 into tiny particles that circulate through the body and weaken immunotherapy\u2019s impact. Scientists in Japan discovered that a little-known protein, UBL3, controls this process\u2014and surprisingly, common cholesterol-lowering drugs called statins can shut it down.<\/p>\n<hr>\n<p>\n<strong>Source:<\/strong><br \/>\n<a href=\"https:\/\/www.sciencedaily.com\/releases\/2026\/01\/260128075323.htm\" target=\"_blank\" rel=\"noopener noreferrer\"><br \/>\nwww.sciencedaily.com<br \/>\n<\/a>\n<\/p>\n<p style=\"font-size:13px;color:#666;\">\n<strong>Medical Disclaimer:<\/strong><br \/>\nThis content is shared for informational and educational purposes only.<br \/>\nIt does not constitute medical, legal, or policy advice.<br \/>\nHealthcare decisions should always be made in consultation with qualified professionals.\n<\/p>\n<p><br \/>\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cancer immunotherapy has been a game-changer, but many tumors still find ways to slip past the immune system. New research reveals a hidden trick: cancer cells can package the immune-blocking protein PD-L1 into tiny particles that circulate through the body and weaken immunotherapy\u2019s impact. Scientists in Japan discovered that a little-known protein, UBL3, controls this [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":26562,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[171],"tags":[1749,17376,11060,13717,17375],"class_list":["post-26561","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-conditions","tag-cancer","tag-fails","tag-hidden","tag-immunotherapy","tag-reason"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/26561","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26561"}],"version-history":[{"count":0,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/26561\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/media\/26562"}],"wp:attachment":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26561"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26561"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26561"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}