{"id":18968,"date":"2025-12-25T11:33:09","date_gmt":"2025-12-25T11:33:09","guid":{"rendered":"https:\/\/pickbydoc.com\/research-supports-moving-away-from-race-as-a-risk-factor\/"},"modified":"2025-12-25T11:33:09","modified_gmt":"2025-12-25T11:33:09","slug":"research-supports-moving-away-from-race-as-a-risk-factor","status":"publish","type":"post","link":"https:\/\/pickbydoc.com\/?p=18968","title":{"rendered":"Research supports moving away from race as a risk factor"},"content":{"rendered":"

In a 2021 American Family Physician<\/i> editorial<\/a> on the dangers of incorporating a patient\u2019s race into medical decision-making, Dr. Bonzo Reddick observed, \u201cAlthough we may hear about biologic or genetic differences between races, there is more variation within<\/i> races than there is between them.\u201d A recent landmark report<\/a> from the National Institutes of Health\u2019s All of Us<\/i> Research Program<\/a> compared self-identified race and ethnicity categories to continental and subcontinental genetic variation. Analyzing about 2 million common variants in the genomes of more than 230,000 unrelated participants, they found that \u201cparticipants within self-identified race and ethnicity groups exhibit gradients of genetic variation rather than discrete clusters.\u201d<\/p>\n

Among White participants, 8% were found to have some South Asian ancestry, whereas smaller percentages had more than 50% African or Native American ancestry. Similarly, 1 in 100 self-identified Black participants had more than 50% European ancestry. The study also found notable regional differences in ancestry percentages among self-identified Black, Hispanic, and White participants. The researchers concluded that these gradients reflect \u201cthe historical impacts of US colonization, the transatlantic slave trade, and recent migrations\u201d and \u201cdemonstrate that social constructs of race and ethnicity do not accurately reflect underlying genetic variation.\u201d<\/p>\n

Maternal race\u2014specifically, Black race\u2014is associated with increased risk for the development of preeclampsia. In its 2021 recommendation statement<\/a> on aspirin to prevent preeclampsia and related morbidity and mortality, the US Preventive Services Task Force included Black race as a moderate risk factor, although it noted that it was a proxy for \u201cenvironmental, social, and historical inequities, \u2026 not biological propensities.\u201d However, a multicenter cohort study<\/a> in JAMA Network Open<\/i> found that Black race, similar to other moderate risks such as nulliparity, maternal age older than 35 years, and body mass index above 30, was not clearly associated with preeclampsia in the absence of a high risk factor (eg, chronic hypertension).<\/p>\n

Finally, a narrative article<\/a> in the New England Journal of Medicine<\/i> traced the historical debate over race-based hemoglobin thresholds that began in the 1970s, when epidemiologic analyses showed that on average, Black children\u2019s serum hemoglobin levels were 0.5 g\/dL lower than those of White children. Did this disparity reflect inherent biological differences between races or differences in nutrition? Should it support race-based definitions of normal hemoglobin levels? Although some analyses accounting for socioeconomic status and diet no longer found significant racial differences, conflicting guidance from the Institute of Medicine (now the National Academy of Medicine) and the Centers for Disease Control and Prevention persisted into the early 2000s. Today, the World Health Organization, American Academy of Pediatrics, and American College of Obstetricians and Gynecologists all recommend against using race-adjusted cutoffs for diagnosing anemia.<\/p>\n

<\/div>\n
**<\/div>\n
<\/div>\n
This post first appeared on the AFP<\/i> Community Blog<\/a>.<\/div>\n

Read full article at source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

In a 2021 American Family Physician editorial on the dangers of incorporating a patient\u2019s race into medical decision-making, Dr. Bonzo Reddick observed, \u201cAlthough we may hear about biologic or genetic differences between races, there is more variation within races than there is between them.\u201d A recent landmark report from the National Institutes of Health\u2019s All […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1747],"tags":[],"class_list":["post-18968","post","type-post","status-publish","format-standard","hentry","category-fitness-lifestyle"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/18968","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18968"}],"version-history":[{"count":0,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=\/wp\/v2\/posts\/18968\/revisions"}],"wp:attachment":[{"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18968"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18968"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pickbydoc.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18968"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}