Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer
Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination ...
Tag: pancreatic
Toward improved early detection of pancreatic cancer
Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving ...
New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy
A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest ...
Pancreatic cancer immune map provides clues for precision treatment targeting
Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be ...
Pancreatic cancer: Study finds most early staging inaccurate
Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new ...
New 3D technique reveals precancerous pancreatic lesions
Researchers have developed a 3D genomic profiling technique to identify small precancerous lesions in the pancreas -- called pancreatic intraepithelial ...
Breaking down barriers: ROCK2 inhibition facilitates drug delivery in fibrotic pancreatic cancer
Scientists developed a human pancreatic cancer fibrotic barrier 3D cell-culture model to assess treatments for pancreatic ductal adenocarcinoma. By targeting ...
Age-related changes in fibroblast cells promote pancreatic cancer growth and spread
Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in ...
Deregulation of alternative RNA splicing promotes pancreatic cancer progression and metastasis
In a new study, researchers demonstrate that deregulation of a protein called RBFOX2, involved in RNA splicing, contributes to the ...
How drugs can target the thick 'scar tissue' of pancreatic cancer
Researchers discovered how anti-cancer drugs called HDAC inhibitors help treat pancreatic cancer by altering scar tissue (fibroblast) development. The findings ...